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Mechanisms and consequences of casein kinase II and ankyrin-3 regulation of the epithelial Na(+) channel
Activity of the Epithelial Na(+) Channel (ENaC) in the distal nephron fine-tunes renal sodium excretion. Appropriate sodium excretion is a key factor in the regulation of blood pressure. Consequently, abnormalities in ENaC function can cause hypertension. Casein Kinase II (CKII) phosphorylates ENaC....
Autores principales: | Abd El-Aziz, Tarek Mohamed, Soares, Antonio G., Mironova, Elena, Boiko, Nina, Kaur, Amanpreet, Archer, Crystal R., Stockand, James D., Berman, Jonathan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285517/ https://www.ncbi.nlm.nih.gov/pubmed/34272444 http://dx.doi.org/10.1038/s41598-021-94118-3 |
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