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Correlation of membrane protein conformational and functional dynamics

Conformational changes in ion channels lead to gating of an ion-conductive pore. Ion flux has been measured with high temporal resolution by single-channel electrophysiology for decades. However, correlation between functional and conformational dynamics remained difficult, lacking experimental tech...

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Detalles Bibliográficos
Autores principales: Sanganna Gari, Raghavendar Reddy, Montalvo‐Acosta, Joel José, Heath, George R., Jiang, Yining, Gao, Xiaolong, Nimigean, Crina M., Chipot, Christophe, Scheuring, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285522/
https://www.ncbi.nlm.nih.gov/pubmed/34272395
http://dx.doi.org/10.1038/s41467-021-24660-1