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NRG4-ErbB4 signaling represses proinflammatory macrophage activity

Macrophages are critical mediators of intestinal defense and homeostasis. However, uncontrolled proinflammatory macrophage activity may contribute to chronic conditions such as inflammatory bowel disease. Currently, the regulatory feedback mechanisms restraining proinflammatory cytokine production i...

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Detalles Bibliográficos
Autores principales: Schumacher, Michael A., Dennis, Isabella C., Liu, Cambrian Y., Robinson, Cache, Shang, Judie, Bernard, Jessica K., Washington, M. Kay, Polk, D. Brent, Frey, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285586/
https://www.ncbi.nlm.nih.gov/pubmed/33826403
http://dx.doi.org/10.1152/ajpgi.00296.2020