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Remdesivir shifts circadian rhythmicity to eveningness; similar to the most prevalent chronotype in ADHD

Circadian clocks control immunity and virus replication, as well as pharmacokinetics and efficacy therapeutics. The aim of this study was to investigate the extent of these relationships by measuring circadian gene expression in primary human-derived dermal fibroblast cultures (HDF) after remdesivir...

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Detalles Bibliográficos
Autores principales: Faltraco, Frank, Palm, Denise, Coogan, Andrew, Uzoni, Adriana, Duwe, Isabell, Simon, Frederick, Tucha, Oliver, Thome, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285716/
https://www.ncbi.nlm.nih.gov/pubmed/34273024
http://dx.doi.org/10.1007/s00702-021-02375-3