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Remdesivir shifts circadian rhythmicity to eveningness; similar to the most prevalent chronotype in ADHD
Circadian clocks control immunity and virus replication, as well as pharmacokinetics and efficacy therapeutics. The aim of this study was to investigate the extent of these relationships by measuring circadian gene expression in primary human-derived dermal fibroblast cultures (HDF) after remdesivir...
Autores principales: | Faltraco, Frank, Palm, Denise, Coogan, Andrew, Uzoni, Adriana, Duwe, Isabell, Simon, Frederick, Tucha, Oliver, Thome, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285716/ https://www.ncbi.nlm.nih.gov/pubmed/34273024 http://dx.doi.org/10.1007/s00702-021-02375-3 |
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