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Modeling temperature- and Cav3 subtype-dependent alterations in T-type calcium channel mediated burst firing
T-type calcium channels are important regulators of neuronal excitability. The mammalian brain expresses three T-type channel isoforms (Cav3.1, Cav3.2 and Cav3.3) with distinct biophysical properties that are critically regulated by temperature. Here, we test the effects of how temperature affects s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285791/ https://www.ncbi.nlm.nih.gov/pubmed/34274007 http://dx.doi.org/10.1186/s13041-021-00813-7 |