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Altered cholesterol homeostasis in critical illness-induced muscle weakness: effect of exogenous 3-hydroxybutyrate

BACKGROUND: Muscle weakness is a complication of critical illness which hampers recovery. In critically ill mice, supplementation with the ketone body 3-hydroxybutyrate has been shown to improve muscle force and to normalize illness-induced hypocholesterolemia. We hypothesized that altered cholester...

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Detalles Bibliográficos
Autores principales: Goossens, Chloë, Weckx, Ruben, Derde, Sarah, Vander Perre, Sarah, Derese, Inge, Van Veldhoven, Paul P., Ghesquière, Bart, Van den Berghe, Greet, Langouche, Lies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285799/
https://www.ncbi.nlm.nih.gov/pubmed/34274000
http://dx.doi.org/10.1186/s13054-021-03688-1