Impact of cumulative fluid balance on the pharmacokinetics of extended infusion meropenem in critically ill patients with sepsis

BACKGROUND: Meropenem dosing for septic critically patients is difficult due to pathophysiological changes associated with sepsis as well as supportive symptomatic therapies. A prospective single-center study assessed whether fluid retention alters meropenem pharmacokinetics and the achievement of t...

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Detalles Bibliográficos
Autores principales: Pařízková, Renata Černá, Martínková, Jiřina, Havel, Eduard, Šafránek, Petr, Kaška, Milan, Astapenko, David, Bezouška, Jan, Chládek, Jaroslav, Černý, Vladimír
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285835/
https://www.ncbi.nlm.nih.gov/pubmed/34274013
http://dx.doi.org/10.1186/s13054-021-03680-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285835/
https://www.ncbi.nlm.nih.gov/pubmed/34274013
http://dx.doi.org/10.1186/s13054-021-03680-9

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