Hypoimmune induced pluripotent stem cell–derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice

The emerging field of regenerative cell therapy is still limited by the few cell types that can reliably be differentiated from pluripotent stem cells and by the immune hurdle of commercially scalable allogeneic cell therapeutics. Here, we show that gene-edited, immune-evasive cell grafts can surviv...

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Detalles Bibliográficos
Autores principales: Deuse, Tobias, Tediashvili, Grigol, Hu, Xiaomeng, Gravina, Alessia, Tamenang, Annika, Wang, Dong, Connolly, Andrew, Mueller, Christian, Mallavia, Beñat, Looney, Mark R., Alawi, Malik, Lanier, Lewis L., Schrepfer, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285900/
https://www.ncbi.nlm.nih.gov/pubmed/34244428
http://dx.doi.org/10.1073/pnas.2022091118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285900/
https://www.ncbi.nlm.nih.gov/pubmed/34244428
http://dx.doi.org/10.1073/pnas.2022091118

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