Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor

Dynamin oligomerizes into helical filaments on tubular membrane templates and, through constriction, cleaves them in a GTPase-driven way. Structural observations of GTP-dependent cross-bridges between neighboring filament turns have led to the suggestion that dynamin operates as a molecular ratchet...

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Detalles Bibliográficos
Autores principales: Ganichkin, Oleg M., Vancraenenbroeck, Renee, Rosenblum, Gabriel, Hofmann, Hagen, Mikhailov, Alexander S., Daumke, Oliver, Noel, Jeffrey K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285958/
https://www.ncbi.nlm.nih.gov/pubmed/34244431
http://dx.doi.org/10.1073/pnas.2101144118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285958/
https://www.ncbi.nlm.nih.gov/pubmed/34244431
http://dx.doi.org/10.1073/pnas.2101144118

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