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Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor
Dynamin oligomerizes into helical filaments on tubular membrane templates and, through constriction, cleaves them in a GTPase-driven way. Structural observations of GTP-dependent cross-bridges between neighboring filament turns have led to the suggestion that dynamin operates as a molecular ratchet...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285958/ https://www.ncbi.nlm.nih.gov/pubmed/34244431 http://dx.doi.org/10.1073/pnas.2101144118 |