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Identification of immune‐activating metabolite for enhancing T cell therapy of cancer

In this Research Highlight, we summarized the results from a study by Wu et al. published in Nature Cell Biology which uncovered that asparagine (Asn), a non‐essential amino acid in mammalians, is able to enhance the TCR‐mediated activation and efficacy of CD8(+) T cells towards tumour through lymph...

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Detalles Bibliográficos
Autores principales: Cong, Boyi, Cui, Zenghui, Cao, Xuetao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286139/
https://www.ncbi.nlm.nih.gov/pubmed/34004061
http://dx.doi.org/10.1002/cac2.12177