Bioanalysis of niclosamide in plasma using liquid chromatography-tandem mass and application to pharmacokinetics in rats and dogs

Niclosamide, which is an anti-tapeworm drug, was developed in 1958. However, recent studies have demonstrated the antiviral effects of niclosamide against the SARS-CoV-2 virus, which causes COVID-19. In this study, we developed and validated a quantitative analysis method for the determination of ni...

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Detalles Bibliográficos
Autores principales: Choi, Hae-In, Kim, Taeheon, Lee, Seung-Won, Woo Kim, Jin, Ju Noh, Yoon, Kim, Gwan-Young, Jin Park, Hyun-, Chae, Yoon-Jee, Lee, Kyeong-Ryoon, Kim, Soo-Jin, Koo, Tae-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286234/
https://www.ncbi.nlm.nih.gov/pubmed/34332199
http://dx.doi.org/10.1016/j.jchromb.2021.122862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286234/
https://www.ncbi.nlm.nih.gov/pubmed/34332199
http://dx.doi.org/10.1016/j.jchromb.2021.122862

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