DJ-1 inhibits microglial activation and protects dopaminergic neurons in vitro and in vivo through interacting with microglial p65

Parkinson’s disease (PD), one of the most common neurodegenerative disorders, is characterized by progressive neurodegeneration of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). DJ-1 acts essential roles in neuronal protection and anti-neuroinflammatory response, and its los...

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Detalles Bibliográficos
Autores principales: Lin, Zixuan, Chen, Chen, Yang, Dongqin, Ding, Jianqing, Wang, Guanghui, Ren, Haigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286256/
https://www.ncbi.nlm.nih.gov/pubmed/34274951
http://dx.doi.org/10.1038/s41419-021-04002-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286256/
https://www.ncbi.nlm.nih.gov/pubmed/34274951
http://dx.doi.org/10.1038/s41419-021-04002-1

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