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LRIG1, a regulator of stem cell quiescence and a pleiotropic feedback tumor suppressor

LRIG1, leucine-rich repeats and immunoglobulin-like domains protein 1, was discovered more than 20 years ago and has been shown to be downregulated or lost, and to function as a tumor suppressor in several cancers. Another well-reported biological function of LRIG1 is to regulate and help enforce th...

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Detalles Bibliográficos
Autores principales: Ji, Yibing, Kumar, Rahul, Gokhale, Abhiram, Chao, Hseu-Ping, Rycaj, Kiera, Chen, Xin, Li, Qiuhui, Tang, Dean G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286266/
https://www.ncbi.nlm.nih.gov/pubmed/33476721
http://dx.doi.org/10.1016/j.semcancer.2020.12.016