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Plumbagin can potently enhance the activity of xanthine oxidase: in vitro, in vivo and in silico studies
BACKGROUND: Abnormally elevated xanthine oxidase (XO) activity has been verified to cause various pathological processes, such as gout, oxidative stress injury and metabolic syndrome. Thus, XO activators may exhibit above potential toxicological properties. Plumbagin (PLB) is an important active com...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286619/ https://www.ncbi.nlm.nih.gov/pubmed/34274011 http://dx.doi.org/10.1186/s40360-021-00511-z |