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Plumbagin can potently enhance the activity of xanthine oxidase: in vitro, in vivo and in silico studies

BACKGROUND: Abnormally elevated xanthine oxidase (XO) activity has been verified to cause various pathological processes, such as gout, oxidative stress injury and metabolic syndrome. Thus, XO activators may exhibit above potential toxicological properties. Plumbagin (PLB) is an important active com...

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Detalles Bibliográficos
Autores principales: Yue, Liang, Jiang, Nan, Wu, Anguo, Qiu, Wenqiao, Shen, Xin, Qin, Dalian, Li, Hong, Lin, Jing, Liang, Sicheng, Wu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286619/
https://www.ncbi.nlm.nih.gov/pubmed/34274011
http://dx.doi.org/10.1186/s40360-021-00511-z