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GPR110 ligands reduce chronic optic tract gliosis and visual deficit following repetitive mild traumatic brain injury in mice

BACKGROUND: Repetitive mild traumatic brain injury (mTBI) can result in chronic visual dysfunction. G-protein receptor 110 (GPR110, ADGRF1) is the target receptor of N-docosahexaenoylethanolamine (synaptamide) mediating the anti-neuroinflammatory function of synaptamide. In this study, we evaluated...

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Detalles Bibliográficos
Autores principales: Chen, Huazhen, Kevala, Karl, Aflaki, Elma, Marugan, Juan, Kim, Hee-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286622/
https://www.ncbi.nlm.nih.gov/pubmed/34273979
http://dx.doi.org/10.1186/s12974-021-02195-y