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Differential Inhibition of Equilibrative Nucleoside Transporter 1 (ENT1) Activity by Tyrosine Kinase Inhibitors

BACKGROUND AND OBJECTIVES: Equilibrative nucleoside transporter (ENT) 1 is a widely-expressed drug transporter, handling nucleoside analogues as well as endogenous nucleosides. ENT1 has been postulated to be inhibited by some marketed tyrosine kinase inhibitors (TKIs). To obtain insights into this p...

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Detalles Bibliográficos
Autores principales: Jouan, Elodie, Moreau, Amélie, Bruyere, Arnaud, Alim, Karima, Denizot, Claire, Parmentier, Yannick, Fardel, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286641/
https://www.ncbi.nlm.nih.gov/pubmed/34275128
http://dx.doi.org/10.1007/s13318-021-00703-2