SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localization

Structural maintenance of chromosomes flexible hinge domain-containing 1 (SMCHD1) is an epigenetic regulator that mediates gene expression silencing at targeted sites across the genome. Our current understanding of SMCHD1's molecular mechanism, and how substitutions within SMCHD1 lead to the di...

Descripción completa

Detalles Bibliográficos
Autores principales: Gurzau, Alexandra D., Horne, Christopher R., Mok, Yee-Foong, Iminitoff, Megan, Willson, Tracy A., Young, Samuel N., Blewitt, Marnie E., Murphy, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Biochemical Techniques & Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286825/
https://www.ncbi.nlm.nih.gov/pubmed/34109974
http://dx.doi.org/10.1042/BCJ20210278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286825/
https://www.ncbi.nlm.nih.gov/pubmed/34109974
http://dx.doi.org/10.1042/BCJ20210278

Ejemplares similares