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SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localization

Structural maintenance of chromosomes flexible hinge domain-containing 1 (SMCHD1) is an epigenetic regulator that mediates gene expression silencing at targeted sites across the genome. Our current understanding of SMCHD1's molecular mechanism, and how substitutions within SMCHD1 lead to the di...

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Detalles Bibliográficos
Autores principales:	Gurzau, Alexandra D., Horne, Christopher R., Mok, Yee-Foong, Iminitoff, Megan, Willson, Tracy A., Young, Samuel N., Blewitt, Marnie E., Murphy, James M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Biochemical Techniques & Resources
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286825/ https://www.ncbi.nlm.nih.gov/pubmed/34109974 http://dx.doi.org/10.1042/BCJ20210278

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