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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase

The coronavirus disease 2019 (COVID-19) pandemic, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global public health challenge. While the efficacy of vaccines against emerging and future virus variants remains unclear, there is a need for therapeutics. Repurpo...

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Detalles Bibliográficos
Autores principales: Zeng, Jingkun, Weissmann, Florian, Bertolin, Agustina P., Posse, Viktor, Canal, Berta, Ulferts, Rachel, Wu, Mary, Harvey, Ruth, Hussain, Saira, Milligan, Jennifer C., Roustan, Chloe, Borg, Annabel, McCoy, Laura, Drury, Lucy S., Kjaer, Svend, McCauley, John, Howell, Michael, Beale, Rupert, Diffley, John F.X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286831/
https://www.ncbi.nlm.nih.gov/pubmed/34198322
http://dx.doi.org/10.1042/BCJ20210201