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Mapping the substrate specificity of the Plasmodium M1 and M17 aminopeptidases

During malarial infection, Plasmodium parasites digest human hemoglobin to obtain free amino acids for protein production and maintenance of osmotic pressure. The Plasmodium M1 and M17 aminopeptidases are both postulated to have an essential role in the terminal stages of the hemoglobin digestion pr...

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Detalles Bibliográficos
Autores principales: Malcolm, Tess R., Swiderska, Karolina W., Hayes, Brooke K., Webb, Chaille T., Drag, Marcin, Drinkwater, Nyssa, McGowan, Sheena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286833/
https://www.ncbi.nlm.nih.gov/pubmed/34133730
http://dx.doi.org/10.1042/BCJ20210172