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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease

The coronavirus 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread around the world with unprecedented health and socio-economic effects for the global population. While different vaccines are now being made available, very few antiviral drug...

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Detalles Bibliográficos
Autores principales: Milligan, Jennifer C., Zeisner, Theresa U., Papageorgiou, George, Joshi, Dhira, Soudy, Christelle, Ulferts, Rachel, Wu, Mary, Lim, Chew Theng, Tan, Kang Wei, Weissmann, Florian, Canal, Berta, Fujisawa, Ryo, Deegan, Tom, Nagaraj, Hema, Bineva-Todd, Ganka, Basier, Clovis, Curran, Joseph F., Howell, Michael, Beale, Rupert, Labib, Karim, O'Reilly, Nicola, Diffley, John F.X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286836/
https://www.ncbi.nlm.nih.gov/pubmed/34198327
http://dx.doi.org/10.1042/BCJ20210197