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Pharmacokinetics and Biologic Activity of Apixaban in Healthy Dogs

Thrombosis is common in critically ill dogs and causes considerable morbidity and mortality. The direct factor Xa inhibitor apixaban is safe, efficacious, and convenient in humans. This study aimed to determine the pharmacokinetics (PK), bioactivity, protein binding, and bioavailability of apixaban...

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Detalles Bibliográficos
Autores principales: Herrera, Noelle D., Birschmann, Ingvild, Wolny, Monika, Papich, Mark G., Brooks, Marjory B., Goggs, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287028/
https://www.ncbi.nlm.nih.gov/pubmed/34291105
http://dx.doi.org/10.3389/fvets.2021.702821