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Next-Generation HLA Sequence Analysis Uncovers Shared Risk Alleles Between Clinically Distinct Forms of Childhood Uveitis

PURPOSE: Classical alleles of the human leukocyte antigen (HLA) complex have been linked to specific entities of pediatric noninfectious uveitis, yet genetic predisposition encoded by the HLA super-locus across the patient population remains understudied. METHODS: We performed next-generation full-l...

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Detalles Bibliográficos
Autores principales: Wennink, Roos A. W., de Boer, Joke H., Hiddingh, Sanne, Haasnoot, Anne-Mieke J. W., Kalinina Ayuso, Viera, de Hoop, Talitha, van Setten, Jessica, Spierings, Eric, Kuiper, Jonas J. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287043/
https://www.ncbi.nlm.nih.gov/pubmed/34254975
http://dx.doi.org/10.1167/iovs.62.9.19