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Long-Term Decrease of Intraocular Pressure in Rats by Viral Delivery of miR-146a

PURPOSE: To evaluate the effects of miR-146a in trabecular meshwork (TM) cells and on intraocular pressure (IOP) in vivo via viral delivery of miR-146a to the anterior chamber of rat eyes. METHODS: Human TM cells were transfected with miR-146 mimic or inhibitor. Some cells from each group were then...

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Detalles Bibliográficos
Autores principales: Luna, Coralia, Parker, Megan, Challa, Pratap, Gonzalez, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287046/
https://www.ncbi.nlm.nih.gov/pubmed/34254987
http://dx.doi.org/10.1167/tvst.10.8.14