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Airway monocyte modulation relates to tumour necrosis factor dysregulation in neutrophilic asthma

BACKGROUND: Dysregulation of tumour necrosis factor-α (TNF-α) signalling is implicated in neutrophilic asthma. TNF-α signalling involves membrane-bound and soluble ligand (TNF-α) and receptors (TNFRs); however, little is known about how these proteins are altered in asthma. We hypothesised that inte...

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Detalles Bibliográficos
Autores principales: Niessen, Natalie M., Gibson, Peter G., Simpson, Jodie L., Scott, Hayley A., Baines, Katherine J., Fricker, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287135/
https://www.ncbi.nlm.nih.gov/pubmed/34291112
http://dx.doi.org/10.1183/23120541.00131-2021