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Minocycline Treatment Reduces Mass and Force Output From Fast-Twitch Mouse Muscles and Inhibits Myosin Production in C2C12 Myotubes

Minocycline, a tetracycline-class of antibiotic, has been tested with mixed effectiveness on neuromuscular disorders such as amyotrophic lateral sclerosis, autoimmune neuritis and muscular dystrophy. The independent effect of minocycline on skeletal muscle force production and signalling remain poor...

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Detalles Bibliográficos
Autores principales: Kiriaev, Leonit, Perry, Ben D., Mahns, David A., Shortland, Peter J., Redwan, Asma, Morley, John W., Head, Stewart I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287211/
https://www.ncbi.nlm.nih.gov/pubmed/34290621
http://dx.doi.org/10.3389/fphys.2021.696039