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Downregulation of LEF1 Impairs Myeloma Cell Growth Through Modulating CYLD/NF-κB Signaling

Aberrant expression of lymphoid enhancer-binding factor-1 (LEF1) has been identified in various hematological malignancies including multiple myeloma (MM). However, the exact role of LEF1 in MM remains largely unknown. Here, we showed that knockdown of LEF1 could apparently impair the proliferation,...

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Detalles Bibliográficos
Autores principales: Zhang, Guihua, Miao, Faan, Liu, Kaige, Wu, Jinyan, Xu, Jinge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287265/
https://www.ncbi.nlm.nih.gov/pubmed/34269120
http://dx.doi.org/10.1177/15330338211034270