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p63 and p53: Collaborative Partners or Dueling Rivals?

The tumor suppressor p53 and its oncogenic sibling p63 (ΔNp63) direct opposing fates in tumor development. These paralog proteins are transcription factors that elicit their tumor suppressive and oncogenic capacity through the regulation of both shared and unique target genes. Both proteins predomin...

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Detalles Bibliográficos
Autores principales: Woodstock, Dana L., Sammons, Morgan A., Fischer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287303/
https://www.ncbi.nlm.nih.gov/pubmed/34291055
http://dx.doi.org/10.3389/fcell.2021.701986