Valproic acid Suppresses Breast Cancer Cell Growth Through Triggering Pyruvate Kinase M2 Isoform Mediated Warburg Effect

Energy metabolism programming is a hallmark of cancer, and serves as a potent target of cancer therapy. Valproic acid (VPA), a broad Class I histone deacetylases (HDACs) inhibitor, has been used as a therapeutic agent for cancer. However, the detail mechanism about the potential role of VPA on the W...

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Detalles Bibliográficos
Autores principales: Li, Zhen, Yang, Lina, Zhang, Shuai, Song, Jiaqi, Sun, Huanran, Shan, Changliang, Wang, Dan, Liu, Shuangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287349/
https://www.ncbi.nlm.nih.gov/pubmed/34263655
http://dx.doi.org/10.1177/09636897211027524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287349/
https://www.ncbi.nlm.nih.gov/pubmed/34263655
http://dx.doi.org/10.1177/09636897211027524

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