d-Pinitol protects against endoplasmic reticulum stress and apoptosis in hepatic ischemia-reperfusion injury via modulation of AFT4-CHOP/GRP78 and caspase-3 signaling pathways

Hepatic ischemia-reperfusion injury (IRI) is a major unavoidable clinical problem often accompanying various liver surgery and transplantation. d-Pinitol, a cyclic polyol, exhibits hepatoprotective efficacy. The objective of this study is to determine the possible mechanism of action of pinitol agai...

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Detalles Bibliográficos
Autores principales: Yan, Lei, Luo, Heng, Li, Xingsheng, Li, Yongyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287360/
https://www.ncbi.nlm.nih.gov/pubmed/34275383
http://dx.doi.org/10.1177/20587384211032098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287360/
https://www.ncbi.nlm.nih.gov/pubmed/34275383
http://dx.doi.org/10.1177/20587384211032098

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