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CCR2 Deficiency Impairs Ly6C(lo) and Ly6C(hi) Monocyte Responses in Orientia tsutsugamushi Infection

Orientia (O.) tsutsugamushi, the causative agent of scrub typhus, is a neglected, obligate intracellular bacterium that has a prominent tropism for monocytes and macrophages. Complications often involve the lung, where interstitial pneumonia is a typical finding. The severity of scrub typhus in huma...

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Detalles Bibliográficos
Autores principales: Petermann, Michael, Orfanos, Zacharias, Sellau, Julie, Gharaibeh, Mohammad, Lotter, Hannelore, Fleischer, Bernhard, Keller, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287586/
https://www.ncbi.nlm.nih.gov/pubmed/34290699
http://dx.doi.org/10.3389/fimmu.2021.670219