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Tumor rejection in Cblb(−/−) mice depends on IL-9 and Th9 cells

BACKGROUND: Casitas B lymphoma-b (Cbl-b) is a central negative regulator of cytotoxic T and natural killer (NK) cells and functions as an intracellular checkpoint in cancer. In particular, Th9 cells support mast cell activation, promote dendritic cell recruitment, enhance the cytolytic function of c...

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Detalles Bibliográficos
Autores principales: Schanz, Oliver, Cornez, Isabelle, Yajnanarayana, Sowmya Parampalli, David, Friederike Sophie, Peer, Sebastian, Gruber, Thomas, Krawitz, Peter, Brossart, Peter, Heine, Annkristin, Landsberg, Jenny, Baier, Gottfried, Wolf, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287598/
https://www.ncbi.nlm.nih.gov/pubmed/34272310
http://dx.doi.org/10.1136/jitc-2021-002889