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Immunogenomic determinants of tumor microenvironment correlate with superior survival in high-risk neuroblastoma

BACKGROUND: Tumor-infiltrating CD8(+) T cells and neoantigens are predictors of a favorable prognosis and response to immunotherapy with checkpoint inhibitors in many types of adult cancer, but little is known about their role in pediatric malignancies. Here, we analyzed the prognostic strength of T...

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Detalles Bibliográficos
Autores principales: Bao, Riyue, Spranger, Stefani, Hernandez, Kyle, Zha, Yuanyuan, Pytel, Peter, Luke, Jason J, Gajewski, Thomas F, Volchenboum, Samuel L, Cohn, Susan L, Desai, Ami V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287618/
https://www.ncbi.nlm.nih.gov/pubmed/34272305
http://dx.doi.org/10.1136/jitc-2021-002417