Pharmacological inhibition of the PI3K/PTEN/Akt and mTOR signalling pathways limits follicle activation induced by ovarian cryopreservation and in vitro culture

BACKGROUND: Cryopreservation and transplantation of ovarian tissue (OTCTP) represent a promising fertility preservation technique for prepubertal patients or for patients requiring urgent oncological management. However, a major obstacle of this technique is follicle loss due to, among others, accel...

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Detalles Bibliográficos
Autores principales: Terren, Carmen, Nisolle, Michelle, Munaut, Carine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287691/
https://www.ncbi.nlm.nih.gov/pubmed/34275490
http://dx.doi.org/10.1186/s13048-021-00846-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287691/
https://www.ncbi.nlm.nih.gov/pubmed/34275490
http://dx.doi.org/10.1186/s13048-021-00846-5

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