CYP3A5 Genotype-Dependent Drug-Drug Interaction Between Tacrolimus and Nifedipine in Chinese Renal Transplant Patients

Purpose: The drug-drug interactions (DDIs) of tacrolimus greatly contributed to pharmacokinetic variability. Nifedipine, frequently prescribed for hypertension, is a competitive CYP3A5 inhibitor which can inhibit tacrolimus metabolism. The objective of this study was to investigate whether CYP3A5 ge...

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Detalles Bibliográficos
Autores principales: Yang, Yilei, Huang, Xin, Shi, Yinping, Yang, Rui, Shi, Haiyan, Yang, Xinmei, Hao, Guoxiang, Zheng, Yi, Wang, Jianning, Su, Lequn, Li, Yan, Zhao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287726/
https://www.ncbi.nlm.nih.gov/pubmed/34290611
http://dx.doi.org/10.3389/fphar.2021.692922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287726/
https://www.ncbi.nlm.nih.gov/pubmed/34290611
http://dx.doi.org/10.3389/fphar.2021.692922

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