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CircFBXL5 promotes the 5-FU resistance of breast cancer via modulating miR-216b/HMGA2 axis

BACKGROUND: Circular RNAs (circRNAs) have been confirmed to be relevant to the 5-fluorouracil (5-FU) resistance of breast cancer. Nevertheless, how and whether circRNA F-box and leucine-rich repeat protein 5 (circFBXL5) regulates the 5-FU resistance of breast cancer is uncertain. This study aims to...

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Detalles Bibliográficos
Autores principales: Zhu, Mingzhi, Wang, Yanyan, Wang, Fang, Li, Lin, Qiu, Xinguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287742/
https://www.ncbi.nlm.nih.gov/pubmed/34281530
http://dx.doi.org/10.1186/s12935-021-02088-3