The ESCRT-III protein VPS4, but not CHMP4B or CHMP2B, is pathologically increased in familial and sporadic ALS neuronal nuclei

Nuclear pore complex injury has recently emerged as an early and significant contributor to familial and sporadic ALS disease pathogenesis. However, the molecular events leading to this pathological phenomenon characterized by the reduction of specific nucleoporins from neuronal nuclear pore complex...

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Detalles Bibliográficos
Autores principales: Coyne, Alyssa N., Rothstein, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287756/
https://www.ncbi.nlm.nih.gov/pubmed/34281622
http://dx.doi.org/10.1186/s40478-021-01228-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287756/
https://www.ncbi.nlm.nih.gov/pubmed/34281622
http://dx.doi.org/10.1186/s40478-021-01228-0

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