Claudin-7 deficiency promotes stemness properties in colorectal cancer through Sox9-mediated Wnt/β-catenin signalling

BACKGROUND: Colorectal cancer (CRC) is a common malignant tumour of the digestive tract that is characterized by high patient morbidity and mortality rates. Claudin-7 (Cldn7), a tight junction protein, was recently reported to function as a candidate tumour suppressor gene in CRC. Our previous study...

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Detalles Bibliográficos
Autores principales: Xu, Chang, Ding, Yu-han, Wang, Kun, Hao, Mengdi, Li, Huimin, Ding, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287764/
https://www.ncbi.nlm.nih.gov/pubmed/34281572
http://dx.doi.org/10.1186/s12967-021-02983-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287764/
https://www.ncbi.nlm.nih.gov/pubmed/34281572
http://dx.doi.org/10.1186/s12967-021-02983-3

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