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Meningitic Escherichia coli α-hemolysin aggravates blood–brain barrier disruption via targeting TGFβ1-triggered hedgehog signaling

Bacterial meningitis is a life-threatening infectious disease with severe neurological sequelae and a high mortality rate, in which Escherichia coli is one of the primary Gram-negative etiological bacteria. Meningitic E. coli infection is often accompanied by an elevated blood–brain barrier (BBB) pe...

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Detalles Bibliográficos
Autores principales: Fu, Jiyang, Li, Liang, Huo, Dong, Yang, Ruicheng, Yang, Bo, Xu, Bojie, Yang, Xiaopei, Dai, Menghong, Tan, Chen, Chen, Huanchun, Wang, Xiangru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287823/
https://www.ncbi.nlm.nih.gov/pubmed/34281571
http://dx.doi.org/10.1186/s13041-021-00826-2