QPX7728, An Ultra-Broad-Spectrum B-Lactamase Inhibitor for Intravenous and Oral Therapy: Overview of Biochemical and Microbiological Characteristics

QPX7728 is a novel β-lactamase inhibitor (BLI) that belongs to a class of cyclic boronates. The first member of this class, vaborbactam, is a BLI in the recently approved Vabomere (meropenem-vaborbactam). In this paper we provide the overview of the biochemical, structural and microbiological studie...

Descripción completa

Detalles Bibliográficos
Autores principales: Lomovskaya, Olga, Tsivkovski, Ruslan, Sun, Dongxu, Reddy, Raja, Totrov, Maxim, Hecker, Scott, Griffith, David, Loutit, Jeffery, Dudley, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287861/
https://www.ncbi.nlm.nih.gov/pubmed/34290688
http://dx.doi.org/10.3389/fmicb.2021.697180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287861/
https://www.ncbi.nlm.nih.gov/pubmed/34290688
http://dx.doi.org/10.3389/fmicb.2021.697180

Ejemplares similares