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deepBlink: threshold-independent detection and localization of diffraction-limited spots

Detection of diffraction-limited spots in single-molecule microscopy images is traditionally performed with mathematical operators designed for idealized spots. This process requires manual tuning of parameters that is time-consuming and not always reliable. We have developed deepBlink, a neural net...

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Detalles Bibliográficos
Autores principales: Eichenberger, Bastian Th, Zhan, YinXiu, Rempfler, Markus, Giorgetti, Luca, Chao, Jeffrey A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287908/
https://www.ncbi.nlm.nih.gov/pubmed/34197605
http://dx.doi.org/10.1093/nar/gkab546