The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid–liquid phase separation

Liquid–liquid phase separation (LLPS) of proteins and RNAs has emerged as the driving force underlying the formation of membrane-less organelles. Such biomolecular condensates have various biological functions and have been linked to disease. The protein Fused in Sarcoma (FUS) undergoes LLPS and mut...

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Detalles Bibliográficos
Autores principales: Reber, Stefan, Jutzi, Daniel, Lindsay, Helen, Devoy, Anny, Mechtersheimer, Jonas, Levone, Brunno Rocha, Domanski, Michal, Bentmann, Eva, Dormann, Dorothee, Mühlemann, Oliver, Barabino, Silvia M L, Ruepp, Marc-David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287939/
https://www.ncbi.nlm.nih.gov/pubmed/34233002
http://dx.doi.org/10.1093/nar/gkab582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287939/
https://www.ncbi.nlm.nih.gov/pubmed/34233002
http://dx.doi.org/10.1093/nar/gkab582

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