rigrag: high-resolution mapping of genic targeting preferences during HIV-1 integration in vitro and in vivo

HIV-1 integration favors recurrent integration gene (RIG) targets and genic proviruses can confer cell survival in vivo. However, the relationship between initial RIG integrants and how these evolve in patients over time are unknown. To address these shortcomings, we built phenomenological models of...

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Detalles Bibliográficos
Autores principales: Bedwell, Gregory J, Jang, Sooin, Li, Wen, Singh, Parmit K, Engelman, Alan N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Data Resources and Analyses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287940/
https://www.ncbi.nlm.nih.gov/pubmed/34165568
http://dx.doi.org/10.1093/nar/gkab514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287940/
https://www.ncbi.nlm.nih.gov/pubmed/34165568
http://dx.doi.org/10.1093/nar/gkab514

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