Cargando…
Cell-free genomics reveal intrinsic, cooperative and competitive determinants of chromatin interactions
Metazoan transcription factors distinguish their response elements from a large excess of similar sequences. We explored underlying principles of DNA shape read-out and factor cooperativity in chromatin using a unique experimental system. We reconstituted chromatin on Drosophila genomes in extracts...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287947/ https://www.ncbi.nlm.nih.gov/pubmed/34181732 http://dx.doi.org/10.1093/nar/gkab558 |