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Cell-free genomics reveal intrinsic, cooperative and competitive determinants of chromatin interactions

Metazoan transcription factors distinguish their response elements from a large excess of similar sequences. We explored underlying principles of DNA shape read-out and factor cooperativity in chromatin using a unique experimental system. We reconstituted chromatin on Drosophila genomes in extracts...

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Detalles Bibliográficos
Autores principales: Eggers, Nikolas, Becker, Peter B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287947/
https://www.ncbi.nlm.nih.gov/pubmed/34181732
http://dx.doi.org/10.1093/nar/gkab558