Assembly of higher-order SMN oligomers is essential for metazoan viability and requires an exposed structural motif present in the YG zipper dimer

Protein oligomerization is one mechanism by which homogenous solutions can separate into distinct liquid phases, enabling assembly of membraneless organelles. Survival Motor Neuron (SMN) is the eponymous component of a large macromolecular complex that chaperones biogenesis of eukaryotic ribonucleop...

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Detalles Bibliográficos
Autores principales: Gupta, Kushol, Wen, Ying, Ninan, Nisha S, Raimer, Amanda C, Sharp, Robert, Spring, Ashlyn M, Sarachan, Kathryn L, Johnson, Meghan C, Van Duyne, Gregory D, Matera, A Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287954/
https://www.ncbi.nlm.nih.gov/pubmed/34181727
http://dx.doi.org/10.1093/nar/gkab508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287954/
https://www.ncbi.nlm.nih.gov/pubmed/34181727
http://dx.doi.org/10.1093/nar/gkab508

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