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Circular L-RNA aptamer promotes target recognition and controls gene activity

Rational design of aptamers to incorporate unnatural nucleotides and special chemical moieties can expand their functional complexity and diversity. Spiegelmer (L-RNA aptamer) is a unique class of aptamer that is composed of unnatural L-RNA nucleotides, and so far there are limited L-RNA aptamer can...

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Detalles Bibliográficos
Autores principales: Ji, Danyang, Lyu, Kaixin, Zhao, Haizhou, Kwok, Chun Kit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287958/
https://www.ncbi.nlm.nih.gov/pubmed/34233000
http://dx.doi.org/10.1093/nar/gkab593