Post-Translational Modifications Modulate Proteinopathies of TDP-43, FUS and hnRNP-A/B in Amyotrophic Lateral Sclerosis

It has been shown that protein low-sequence complexity domains (LCDs) induce liquid-liquid phase separation (LLPS), which is responsible for the formation of membrane-less organelles including P-granules, stress granules and Cajal bodies. Proteins harbouring LCDs are widely represented among RNA bin...

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Detalles Bibliográficos
Autores principales: Farina, Stefania, Esposito, Francesca, Battistoni, Martina, Biamonti, Giuseppe, Francia, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287968/
https://www.ncbi.nlm.nih.gov/pubmed/34291086
http://dx.doi.org/10.3389/fmolb.2021.693325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287968/
https://www.ncbi.nlm.nih.gov/pubmed/34291086
http://dx.doi.org/10.3389/fmolb.2021.693325

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