Tumor‐derived exosomal BCYRN1 activates WNT5A/VEGF‐C/VEGFR3 feedforward loop to drive lymphatic metastasis of bladder cancer

BACKGROUND: Patients with lymph node (LN) metastatic bladder cancer (BCa) present with extremely poor prognosis. BCa‐derived exosomes function as crucial bioactive cargo carriers to mediate the signal transduction in tumor microenvironment triggering tumor metastasis. However, the mechanisms underly...

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Detalles Bibliográficos
Autores principales: Zheng, Hanhao, Chen, Changhao, Luo, Yuming, Yu, Min, He, Wang, An, Mingjie, Gao, Bowen, Kong, Yao, Ya, Yiyao, Lin, Yan, Li, Yuting, Xie, Keji, Huang, Jian, Lin, Tianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288020/
https://www.ncbi.nlm.nih.gov/pubmed/34323412
http://dx.doi.org/10.1002/ctm2.497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288020/
https://www.ncbi.nlm.nih.gov/pubmed/34323412
http://dx.doi.org/10.1002/ctm2.497

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